In vivo Ab (細胞/動物實驗專用一抗)-Antibody-盟基生物科技股份有限公司

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Primary Antibody (一級抗體)

In vivo Ab (細胞/動物實驗專用一抗)

In vivo Ab (細胞/動物實驗專用一抗)

Primary Antibody (一級抗體)

In vivo Ab (細胞/動物實驗專用一抗)

高純度 & 低內毒素抗體，可用於細胞和動物實驗，抑制生長因子或免疫蛋白。

點我詢問
抗體除了可用來進行免疫螢光染色 (Immunofluorescence)、流式細胞分析 (Flow cytometry)、西方墨點法 (Western blotting) 等實驗，也可用於細胞和動物。藉由結合細胞表面的特殊受體而抑制其功能，觀察此受體對於細胞或動物的影響。這類的抗體需要高純度、低內毒素、無添加物，避免對細胞和動物造成傷害。Selleckchem 提供 In Vivo Antibody，可大量提供至克等級 (gram)。

一、產品介紹
Selleckchem 為小分子藥物 (small molecule compounds/inhibitors) 供應商，超過3000種小分子抑制劑應用於細胞訊息傳遞路徑。新推出的 In Vivo antibody 專門用於細胞或動物實驗，可用來抑制 growth factor receptor 而抑制生長、阻擋 immunocheckpoint receptor 而活化免疫細胞、中和細胞因子抑制其作用等功能。此產品僅供研究用使用，禁止用於人體。


二、產品優點
1. 高純度 (>95%)
2. 低內毒素 (<2EU/mg)
3. 划算大包裝 (>5mg)
4. 單純 PBS 配方 (pH 7.4)，無添加物 Preservative, Stabilizer, Carrier
5. 以0.2um filter過濾，確保無菌


三、產品資訊
包含 Selleckchem 自己研發的 InVivo Antibody 和已經為市面上抗體藥的 Therapeutic Antibody，皆穩定儲存於4℃至少一年。

表一：InVivo Antibody 訂購資訊
目標蛋白 產品名稱 抗體 isotype 貨號 應用
CD8α Anti-mouse CD8α-InVivo Rat IgG2b, κ A2102 In vivo CD8+ T cell depletion,WB
IL-17A Anti-mouse IL-17A-InVivo Mouse IgG1, κ A2120 in vivo IL-17A neutralization
IFNAR-1 Anti-mouse IFNAR-1-InVivo Mouse IgG1, κ A2121 in vivo IFNAR-1 blockade, in vitro IFNAR-1 blockade, WB
IL-6 Anti-mouse IL-6-InVivo Rat IgG1, κ A2118 in vivo IL-6 neutralization
PD-L1 Anti-mouse PD-L1 (B7-H1)-InVivo Rat,IgG2b, κ A2115 in vivo PD-L1 blockade,IF,IHC (frozen),FCM,WB
CD4 Anti-mouse CD4-InVivo Rat IgG2b,κ A2101 In vivo CD4+ T cell depletion,FCM,WB,IP,IHC
CTLA-4 Anti-mouse CTLA-4 (CD152)-InVivo Armenian Hamster IgG A2103 in vivo/vitro CTLA-4 neutralization, FCM,WB
IFNγ Anti-mouse IFNγ-InVivo Rat IgG1,κ A2105 in vivo/vitro IFNγ neutralization
NK1.1 Anti-mouse NK1.1-InVivo Mouse IgG2a,κ A2114 in vivo NK cell depletion,FCM
CD25 Anti-mouse CD25 (IL-2Rα)-InVivo Rat IgG1,λ A2107 in vivo regulatory T cell depletion,FCM
CD28 Anti-mouse CD28-InVivo Armenian Hamster IgG,κ A2108 in vitro T cell stimulation/activation
IL-4 Anti-mouse IL-4-InVivo Rat IgG1,κ A2109 in vivo/vitro IL-4 neutralization,FCM,WB
CD16/CD32 Anti-mouse CD16/CD32-InVivo Rat IgG2b,κ A2110 in vitro/vivo Fc receptor blocking
TGF-β Anti-human/mouse TGF-β-InVivo Mouse IgG1,κ A2113 in vivo/vitro TGFβ neutralization,WB
X Rat IgG2b isotype control-InVivo Rat IgG2b, κ A2116  
X Rat IgG1 isotype control-InVivo Rat IgG1, κ A2119  
X Mouse IgG2a isotype control-InVivo Mouse,IgG2a, κ A2117  
 
表二：Therapeutic Antibody 訂購資訊
目標蛋白 產品名稱 抗體 isotype 貨號
CD20 Obinutuzumab (anti-CD20) Humanized IgG1 A2023
Rituximab (anti-CD20) Human IgG1 A2009
CD38 Daratumumab (anti-CD38) Human IgG1 A2027
CTLA-4 Ipilimumab (anti-CTLA-4) Human IgG1 A2001
EGFR Cetuximab (anti-EGFR) Human IgG1 A2000
HER2 Trastuzumab (anti-HER2) Human IgG1 A2007
Pertuzumab (anti-HER2) Human IgG1 A2008
IL-6R Tocilizumab (anti-IL-6R) Human IgG1 A2012
IL-6Rα Sarilumab (anti-IL-6Rα) Human IgG1 A2011
IL-17A Secukinumab (anti-IL-17A) Human IgG1 A2025
PD-1 Nivolumab (anti-PD-1) Human IgG4 A2002
Pembrolizumab (anti-PD-1) Human IgG4 A2005
Camrelizumab (anti-PD-1) Human IgG4 A2016
Spartalizumab (anti-PD-1) Human IgG4 A2017
Cemiplimab (anti-PD-1) Human IgG4 A2022
PD-L1 Atezolizumab (anti-PD-L1) Human IgG1 A2004
Durvalumab (anti-PD-L1) Human IgG1 A2013
Avelumab (anti-PD-L1) Human IgG1 A2015
TNF-alpha Adalimumab (anti-TNF-alpha) Human IgG1 A2010
Infliximab (anti-TNF-alpha) Chimeric IgG1 A2019
VEGF Bevacizumab (anti-VEGF) Human IgG1 A2006
VEGFR2 Ramucirumab (anti-VEGFR2) Human IgG1 A2003
IL-12/IL-23 Ustekinumab (anti-IL-12/IL-23) Human IgG1 A2024
RANK ligand Denosumab (anti-RANK ligand) human IgG4 A2020
 

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