小分子抑制劑 (Small Inhibitor)-新冠病毒(SARS-CoV2)研究-盟基生物科技股份有限公司

新冠病毒(SARS-CoV2)研究

小分子抑制劑 (Small Inhibitor)

小分子抑制劑 (Small Inhibitor)

新冠病毒(SARS-CoV2)研究

小分子抑制劑 (Small Inhibitor)

Selleckchem 新整理推出的小分子抑制藥物,具有高潛力可以用來抑制病毒感染、複製和生長。

除了疫苗之外,全世界也正在研究抑制病毒感染、生長、複製的藥物,Selleckchem 整合世界上的研究,整理出多個高潛力小分子藥物,並且附上文獻參考來源,方便大家進行研究。除此之外,還有推出 “Antiviral Compound Library” (#L7000),可一次購買所有可能藥物,進行大量的篩選,快速找出高潛力目標。詳細資訊請參考原廠資料


 
貨號 產品名稱 相關資訊
S3079 Atovaquone Atovaquone is a medication used to treat or prevent for pneumocystis pneumonia, toxoplasmosis, malaria, and babesia.
S1835 Azithromycin Azithromycin is an antibiotic by inhibiting protein synthesis, used for the treatment of bacterial infections.
S5940 Bepotastine Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor that is indicated in allergic rhinitis, urticaria, and pruritus associated with skin disease.
S3037 Bepotastine Besilate Bepotastine is a non-sedating, selective antagonist of histamine 1 (H1) receptor.
S5911 Bictegravir Bictegravir is a novel, potent, once-daily, unboosted inhibitor of HIV-1 integrase.
S3733 Boceprevir Boceprevir is an oral, direct acting hepatitis C virus (HCV) protease inhibitor. It is used in combination with other antiviral agents in the treatment of chronic hepatitis C, genotype 1.
S2874 Camostat Mesilate Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function.
S2853 Carfilzomib (PR-171) Carfilzomib (PR-171) is an irreversible proteasome inhibitor, displayed preferential in vitro inhibitory potency against the ChT-L activity in the β5 subunit, but little or no effect on the PGPH and T-L activities.
S1289 Carmofur Carmofur is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer.
S4157 Chloroquine diphosphate Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator.
S4646 Ciclesonide Ciclesonide is a glucocorticoid used to treat obstructive airway diseases.
S1183 Danoprevir (ITMN-191) Danoprevir(ITMN-191) is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV), inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Phase 2.
S5250 Darunavir Darunavir is a nonpeptidic HIV protease inhibitor, used to treat HIV infection.
S1620 Darunavir Ethanolate Darunavir Ethanolate (DRV) is a nonpeptidic HIV protease inhibitor, used to treat HIV infection.
S3035 Daunorubicin HCl Daunorubicin HCl inhibits both DNA and RNA synthesis and inhibits DNA synthesis.
S1680 Disulfiram Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol.
S6676 Ebselen Ebselen is a small-molecule capsid inhibitor of HIV-1 Replication.
S8969 EIDD-2801 EIDD-2801 is an orally bioavailable prodrug of the ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931) with broad-spectrum antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV.
S7975 Favipiravir (T-705) Favipiravir (T-705) is a potent and selective RNA-dependent RNA polymerase inhibitor, used to treat influenza virus infections.
S4430 Hydroxychloroquine Sulfate Hydroxychloroquine Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.
S9567 Indinavir Sulfate Indinavir sulfate is a specific and potent inhibitor of HIV-1 protease and is widely used in the treatment of AIDS.
S1351 Ivermectin Ivermectin is a glutamate-gated chloride channel (GluCls) activator, used as a broad-spectrum antiparasitic drug.
S1706 Lamivudine Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor, used for treatment of chronic HBV and HIV/AIDS. It works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase.
S7579 Ledipasvir (GS5885) Ledipasvir (GS5885) is a HCV NS5A polymerase inhibitor, used for the treatment of hepatitis C virus infection.
S1380 Lopinavir Lopinavir is a potent HIV protease inhibitor.
S2485 Mitoxantrone 2HCl Mitoxantrone is a type II topoisomerase inhibitor.
S2079 Moexipril HCl Moexipril HCl is a potent orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure.
S1386 Nafamostat Mesylate Nafamostat mesilate is a synthetic serine protease inhibitor, used as an anticoagulant during hemodialysis. Nafamostat mesylate blocks activation of SARS-CoV-2. Nafamostat Mesilate attenuates inflammation and apoptosis.
S4282 Nelfinavir Mesylate Nelfinavir Mesylate is a potent HIV protease inhibitor.
S1759 Pitavastatin Calcium Pitavastatin calcium, a novel member of the medication class of statins, is a calcium salt formulation of pitavastatin which is a highly effective HMG-CoA reductase inhibitor.
S1691 Praziquantel Praziquantel is an anthelmintic effective against flatworms.
S2071 Prulifloxacin (NM441) Prulifloxacin, the prodrug of ulifloxacin, is a broad-spectrum oral fluoroquinolone antibacterial agent.
S7947 PX-12 PX-12 is a potent thioredoxin-1 (Trx-1) inhibitor by irreversibly thioalkylation of Cys73 of Trx-1. Phase 2.
S8932 Remdesivir (GS-5734) Remdesivir,a monophosphoramidate prodrug of an adenosine analog, is an investigational broad-spectrum antiviral agent with in vitro activity against multiple RNA viruses, including Ebola and CoV.
S1185 Ritonavir Ritonavir is a Cytochrome P450 3A and Protease Inhibitor; Also inhibits Cytochrome P450 2D6, P-Glycoprotein and induces Cytochrome P450 2C19, Cytochrome P450 1A2, Cytochrome P450 2C9, Cytochrome P450 2B6 and UDP Glucuronosyltransferases.
S2169 Rosuvastatin Calcium Rosuvastatin Calcium is a competitive inhibitor of HMG-CoA reductase.
S8279 Shikonin Shikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao, a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay.
S2926 TDZD-8 TDZD-8 is a non-ATP competitive GSK-3β inhibitor; minimal inhibitory effect observed on CDK1, casein kinase II, PKA and PKC.
S1538 Telaprevir (VX-950) Telaprevir (VX-950) is an HCV NS3-4A serine protease inhibitor.
S1401 Tenofovir Tenofovir blocks reverse transcriptase and hepatitis B virus infections.
S2823 Tideglusib Tideglusib is an irreversible, non ATP-competitive GSK-3β inhibitor; fails to inhibit kinases with a Cys homologous to Cys-199 located in the active site. Phase 2.
S3724 Velpatasvir Velpatasvir is a second-generation NS5A inhibitor that inhibits hepatitis C viral replication through acting on the crucial "membranous web" that facilitates RNA replication.
 
 
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