重組蛋白 (Recombinant Protein)-新冠病毒(SARS-CoV2)研究-盟基生物科技股份有限公司

新冠病毒(SARS-CoV2)研究

重組蛋白 (Recombinant Protein)

重組蛋白 (Recombinant Protein)

新冠病毒(SARS-CoV2)研究

重組蛋白 (Recombinant Protein)

提供新冠病毒的重組蛋白 (Recombinant Protein),可以當作抗原發展抗體,或是研究病毒和細胞之間的關係。

1. Genscript 重組蛋白
GenScript 因應新型冠狀病毒 (SARS-CoV2、2019-nCoV),提供一系列相關重組蛋白,從完整的 S 蛋白到 RBD、ECD、S1 protein、S2 protein 一應俱全。(詳細資訊請參考原廠網頁)
 
類別 產品名稱 宿主 貨號 包裝
S-ECD SARS-CoV-2 S protein (ECD, His & Flag Tag) Sf9 insect cell Z03481-100 100μg
Z03481-1 1mg
S-RBD SARS-CoV-2 S protein (RBD, His-tagged) Sf9 insect cell Z03479-100 100μg
Z03479-500 500μg
Z03479-1 1mg
HEK293 Z03483-100 100μg
Z03483-1 1mg
SARS-CoV-2 S protein (RBD, Fc-tagged) HEK293 Z03491-100 100μg
Z03491-1 1mg
S1 protein SARS-CoV-2 S1 protein (tag-free) HEK293 Z03501-100 100μg
Z03501-1 1mg
SARS-CoV-2 S1 protein (His-tagged) HEK293 Z03485-100 100μg
Z03485-1 1mg
S2 protein SARS-CoV-2 S2 protein(ECD,FC-tagged) HEK293 Z03495-100 100μg
Z03495-1 1mg
N protein SARS-CoV-2 N protein (tag-free) E.coli Z03488-100 100μg
Z03488-1 1mg
SARS-CoV-2 N protein (His-tagged) E.coli Z03480-100 100μg
Z03480-1 1mg
ACE-2 ACE-2 protein (FC-tagged) HEK293 Z03484-1 1mg
HEK293 Z03484-100 100μg
 

2. Elabscience 重組蛋白
Elabscience 提供全系列的新冠病毒蛋白,包含 S, N, E, NSP protein,以及人類的相關蛋白。(詳細資訊請參考原廠網頁)

(1) 新冠病毒表面蛋白 Spike protein RBD,包含 wild-type 和 mutant。研究證明 RBD 會和人類的 ACE2 結合,進而感染細胞。透過序列多型性分析,RBD 具有高度多變性。在1609 SARS-CoV2 病毒株中,32個病毒株有 RBD 的突變。V367F 突變來自於法國和香港,V483A 和 G476S 突變來自於美國。而研究發現這些突變可能會增加 RBD 和人類 ACE2 的親和力。因此,這些突變有可能會影響到抗體藥和疫苗的效果。
類別 產品名稱 宿主 貨號 包裝
S-RBD wild-type Recombinant 2019-nCoV Spike Protein (RBD) HEK293 Cells PKSR030521 100µg
1mg
Recombinant 2019-nCoV S Protein (RBD, His Tag) HEK293 Cells PKSR030475 50µg
1mg
Recombinant 2019-nCoV Spike Protein (RBD, His Tag) HEK293 Cells PKSR030519 100µg
1mg
Baculovirus-Insect Cells PKSR030499 100µg
1mg
Recombinant 2019-nCoV Spike Protein, Biotinylated (RBD, His Tag) Baculovirus-Insect Cells PKSR030501 20µg
HEK293 Cells PKSR030520 20µg
Recombinant 2019-nCoV Spike Protein (RBD, Fc Tag) HEK293 Cells PKSR030518 100µg
1mg
Recombinant 2019-nCoV Spike Protein (RBD, mFc Tag) HEK293 Cells PKSR030500 100µg
1mg
Recombinant 2019-nCoV S Protein (RBD, mFc Tag) HEK293 Cells PKSR030474 50µg
1mg
Recombinant 2019-nCoV Spike Protein (RBD, rFc Tag) HEK293 Cells PKSR030522 100µg
1mg
Recombinant 2019-nCoV S Protein (RBD-SD1, His Tag) HEK293 Cells PKSR030477 50µg
1mg
Recombinant 2019-nCoV S Protein (RBD-SD1, mFc Tag) HEK293 Cells PKSR030476 50µg
1mg
Recombinant 2019-nCoV S Protein (RBD-SD1, Avi-His Tag) HEK293 Cells PKSR030478 20µg
100µg
S-RBD mutant Recombinant 2019-nCoV Spike Protein (RBD, His Tag)(V367F) HEK293 Cells PKSR030524 100µg
Recombinant 2019-nCoV Spike Protein (RBD, His Tag)(K458R) HEK293 Cells PKSR030525 100µg
Recombinant 2019-nCoV Spike Protein (RBD, His Tag)(F342L) HEK293 Cells PKSR030526 100µg
Recombinant 2019-nCoV Spike Protein (RBD, His Tag)(V483A) HEK293 Cells PKSR030527 100µg
Recombinant 2019-nCoV Spike Protein (RBD, His Tag)(A435S) HEK293 Cells PKSR030528 100µg
Recombinant 2019-nCoV Spike Protein (RBD, His Tag)(N354D) HEK293 Cells PKSR030529 100µg
Recombinant 2019-nCoV Spike Protein (RBD, mFc Tag)(V367F) HEK293 Cells PKSR030523 100µg


(2) 新冠病毒表面蛋白 spike protein (S) 和 envelope protein (E),此部分的 spike protein 為完整 spike protein 或是其他 subunits。
類別 產品名稱 宿主 貨號 包裝
S protein Recombinant 2019-nCoV Spike Protein (His Tag) HEK293 Cells PKSR030490 1mg
Recombinant 2019-nCoV S-trimer Protein (His Tag) HEK293 Cells PKSR030489 50µg
1mg
S-NTD Recombinant 2019-nCoV S Protein (NTD, His Tag) HEK293 Cells PKSR030484 50µg
1mg
S-ECD Recombinant 2019-nCoV S1+S2 Protein (ECD, His Tag) Baculovirus-Insect Cells PKSR030498 100µg
1mg
S1 protein Recombinant 2019-nCoV S1 Protein HEK293 Cells PKSR030481 50µg
1mg
Recombinant 2019-nCoV S1 Protein (His Tag) HEK293 Cells PKSR030482 50µg
1mg
HEK293 Cells PKSR030503 100µg
1mg
Baculovirus-Insect Cells PKSR030514 100µg
1mg
Recombinant 2019-nCoV S1 Protein, Biotinylated (His Tag) HEK293 Cells PKSR030515 20µg
Recombinant 2019-nCoV S1 Protein (Fc Tag) HEK293 Cells PKSR030480 50µg
1mg
HEK293 Cells PKSR030502 100µg
1mg
Recombinant 2019-nCoV S1 Protein (mFc Tag) HEK293 Cells PKSR030479 50µg
1mg
HEK293 Cells PKSR030504 100µg
1mg
S1-CTD Recombinant 2019-nCoV S1 Protein (CTD, His Tag) HEK293 Cells PKSR030483 50µg
  1mg
S2 protein Recombinant 2019-nCoV S2 Protein (Fc Tag) HEK293 Cells PKSR030491 50µg
1mg
Recombinant 2019-nCoV S2 Protein (mFc Tag) Baculovirus-Insect Cells PKSR030516 100µg
S2-ECD Recombinant 2019-nCoV S2 Protein (ECD, His Tag) Baculovirus-Insect Cells PKSR030505 100µg
1mg
Recombinant 2019-nCoV S2 Protein (ECD, Fc Tag) HEK293 Cells PKSR030517 100µg
E protein Recombinant 2019-nCoV Envelope Protein (His Tag) E.coli PKSR030488 1mg
 

(3) 新冠病毒內部的蛋白,和病毒於細胞內部的複製相關,可以做為抑制病毒生長的目標。
類別 產品名稱 宿主 貨號 包裝
N protein Recombinant 2019-nCoV Nucleocapsid Protein (His Tag) E.coli PKSR030485 1mg
Baculovirus-Insect Cells PKSR030497 100µg
1mg
Recombinant 2019-nCoV Nucleocapsid Protein, Biotinylated (His Tag) Baculovirus-Insect Cells PKSR030512 20µg
Recombinant 2019-nCoV NP NTD domain (His Tag) E.coli PKSR030486 1mg
Recombinant 2019-nCoV NP CTD domain Protein E.coli PKSR030487 1mg
Protease Recombinant 2019-nCoV 3C-like Proteinase Protein (His Tag) E.coli PKSR030465 10μg
50μg
Recombinant 2019-nCoV Papain-Like Protease Protein E.coli PKSR030472 10μg
50μg
Recombinant 2019-nCoV Papain-like Protease Protein (His Tag) E.coli PKSR030511 100µg
1mg
Helicase Recombinant 2019-nCoV Helicase Protein (His Tag) E.coli PKSR030466 10μg
50μg
Leader protein Recombinant 2019-nCoV NSP1 Protein (His Tag) E.coli PKSR030467 10μg
50μg
p65 homolog Recombinant 2019-nCoV NSP2 Protein (His Tag) E.coli PKSR030468 10μg
50μg
Growth factor-like peptide Recombinant 2019-nCoV NSP10 Protein (His Tag) E.coli PKSR030471 10μg
50μg
Guanine-N7 methyltransferase Recombinant 2019-nCoV Guanine-N7_meth Protein (His Tag) E.coli PKSR030473 10μg
50μg
Others Recombinant 2019-nCoV NSP7 Protein (His Tag) E.coli PKSR030469 10μg
50μg
Recombinant 2019-nCoV NSP8 Protein (His Tag) E.coli PKSR030470 10μg
50μg
Recombinant 2019-nCoV Methyltransferase / ME Protein (His Tag) E. coli PKSR030513 100µg
 

(4) 人類細胞幫助病毒感染的蛋白,新冠病毒 (SARS-CoV2、2019-nCoV) 透過 S protein 結合細胞的 ACE2,並透過宿主的 Cathepsin B/L 和 CD147 降解 spike protein,幫助病毒釋放核酸進入細胞。因此 Elabscience 也有提供人類細胞和感染的相關蛋白質,幫助感染機制的研究。
類別 產品名稱 宿主 貨號 包裝
ACE-2 Recombinant Human ACE2 Protein (His Tag) HEK293 Cells PKSH032068 10μg
50μg
HEK293 Cells PKSR030508 20µg
100µg
Baculovirus-Insect Cells PKSR030510 20µg
100µg
Recombinant Human ACE2 Protein (Fc Tag) HEK293 Cells PKSR030492 10μg
50μg
Recombinant Human ACE2 Protein (mFc Tag) HEK293 Cells PKSR030494 10μg
50μg
HEK293 Cells PKSR030509 20µg
100µg
Recombinant Human ACE2 Protein (Avi-His Tag) HEK293 Cells PKSR030493 20μg
100μg
CD147 Recombinant Human CD147/Basigin Protein (His Tag) HEK293 Cells PKSH032377 10μg
50μg
Recombinant Mouse CD147/Basigin Protein (His Tag) HEK293 Cells PKSM041223 10μg
50μg
Cathepsin Recombinant Human Cathepsin B/CTSB Protein (His Tag) HEK293 Cells PKSH032179 10μg
50μg
Recombinant Mouse Cathepsin B/CTSB Protein (His Tag) HEK293 Cells PKSM040956 10μg
50μg
Recombinant Human Cathepsin L/CTSL Protein (His Tag) HEK293 Cells PKSH032182 10μg
50μg
Recombinant Mouse Cathepsin L/CTSL Protein His Tag) HEK293 Cells PKSM041247 10μg
50μg
APN Recombinant Human APN Protein (His Tag) HEK293 Cells PKSR030495 10μg
50μg
Recombinant Mouse APN Protein (His Tag) HEK293 Cells PKSR030496 10μg
50μg
 
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